endocannabinoid system for cbd

In this Article we will discuss what exactly is the Endocannabinoid System (ECS) in our bodies and our furry friend’s bodies. More importantly how CBD interacts with our own ECS. With other useful information regarding your ECS.


The ECS is a biological system present in all mammals,  You and your furry friend. It is composed of endocannabinoids (molecules made by your own body), which are neurotransmitters that bind to cannabinoid receptors. These cannabinoid receptors are present throughout central nervous system, brain, and peripheral nervous system. Leading research has identified two key endocannabinoids so far, Anandamide (AEA) and 2-Arachidonovlglyerol (2-AG). These are the cannabinoids all our own bodies produce. Moreover, the main receptors are called CB1 and CB2. 

The Endocannabinoid system’s job is to keep our body in homeostasis, or equilibrium, and it regulates everything from appetite, sleep, sensation, inflammation, libido, mood, fertility, memory, and much more. 

In other words, it regulates all of our normal day to day functions within the body and mind. We all have an ECS as a natural part of our bodies just like your heart or your brain. More importantly, we are discovering how important and vital the ECS is as part of our biological makeup.

What is Homeostasis?

Homeostasis in scientific terms is any self-regulating process by which biological systems tend to maintain stability while adjusting to conditions that are optimal for survival. In short, if homeostasis is successful, life continues; if unsuccessful, disaster or death ensues. The stability attained is actually a dynamic equilibrium, in which continuous change occurs yet relatively uniform conditions prevail.

In simple terms, it is one’s body efforts to keep everything in the proper and right balance to keep functioning. Internally, it succeeds at keeping your body stable and optimal for functioning, no matter what is happening in the external world around you.


The two primary cannabinoid receptors have been identified as: CB1, first cloned in 1990; and CB2, cloned in 1993. CB1 receptors are found predominantly in the brain and nervous system, as well as in peripheral organs and tissues. Now, the brain has roughly 100 billion nerve cells and these cells are in constant communication via synapses. Nerves send signals to these through axons, which are extensions of the nerves. At the synapse, neurotransmitters are released, which cross the synapse and send the signal to the cannabinoid receptors in the endocannabinoid system.

For example, think of your iphone and all your apps. Each one does a certain function, i.e. for email, facebook, or banking. When these are downloaded properly to your phone and you are signed in, they are functioning properly and continuously. Now if you didn’t download one of the apps properly or can’t sign on, then there is a problem, and that is when your ECS kicks in!

Your body functions in the same way. We all have these gauges like in an airplane and our bodies work 24/7 monitoring these levels so we can survive.

Now, when one of these functions is out of whack, your body activates the ECS to help get it back to a normal range so you can function properly.

Two Examples of the ECS at Work

  • You start to get hunger pains in your belly. That is your ECS telling you to eat something because you need fuel to keep functioning.
  • You come down with a fever and because of this your body begins to sweat to try and cool you down. Again, it is our ECS at work. Thank you ECS for keeping me alive!


    The ECS is made up of Three Partsfemaile endocannabinoid system ecs for cbd
male endocannabinoid system ecs for cbd

  1. Receptors primarily CB1 and CB2
  2. Endocannabinoids or Neurotransmitters
  3. Enzymes that aid in the breakdown of Cannabinoids and Endocannabinoids





CBD does not bind to the ECS itself, but rather activates or inhibits other compounds or receptors. I.E. blocking discomfort signals or allowing healthy molecules to enter. In other words, CBD stimulates the proper function of the ECS to increase the production of cannabinoids and preliminary studies have suggested prolonging degradation of endocannabinoids.

Some plants, like Hemp produce a substance similar to endocannabinoids that interact with our own body’s receptors. These phytocannabinoids – plant made cannabinoids – can have a profound effect on the body. While there are many plants that produce substances that act upon cannabinoid receptors, the cannabis plant is the only known to produce cannabidiol (CBD).

Endocannabinoid Deficiency Syndrome

Unfortunately, most western modern diets do not always contain the nutrition required to maintain the endocannabinoid system properly. In cases where nutritional deficiencies or other problems are causing the endocannabinoid system to fail, a person may develop a condition known as “Endocannabinoid Deficiency Syndrome”. This can lead to a variety of symptoms and related conditions. More importantly, with all the vitamins, minerals, and cannabinoids that make up the hemp plant, one can surmise that this can only help this deficiency, which in turn could only help the user get back to an optimal functioning system.


                                                  READ MORE HERE!


Are you Ready to try CBD Oil, but wondering if CBD will cause a psychoactive, mind altering “high” effect?


THE SHORT ANSWER IS NO! CBD is 100% non-psychoactive, meaning it does not negatively impact your mental processes or mind or day to day activities.

There is still much well founded confusion surrounding CBD Oil products and what exactly it is, and does it get you high. Moreover, many think the Hemp plant and Marijuana plant have the same makeup because they are both in the “Cannabis” Family of plants. In this article we will explain what exactly CBD is and dispel the confusion that CBD might get you high. Also, we will discuss the differences in CBD with regards to Hemp and Marijuana Plants.


Cannabidiol (CBD) is a phytocannabinoid discovered in 1940. It accounts for up to 40% of the plant’s extract and is one of 113 identified cannabinoids in cannabis plants. 

The extraction process of CBD from Hemp is used to yield highly concentrated CBD oil that also contains highly nutritious elements, including the 20 amino acids including the nine essential ones, terpenes, omega healthy fatty acids, vitamins B1/B2/B3/B6, Vitamin E, and Vitamin C. Minerals include calcium, magnesium, sulfur, copper, potassium, and phosphorus. Many people use CBD as a preventative daily supplement for maintaining overall health and wellness. While others, use CBD to help for a specific issue.

Hemp CBD vs. Marijuana CBD

CBD itself derived from Hemp or Marijuana has the exact same properties. However, the Hemp plant has low levels of THC 0.3%, as compared to 10-30% THC levels in the Marijuana Plant. Cultivated Hemp has higher levels of CBD within the plant, usually around 30-40%, while the Marijuana plant contains much lower levels of CBD 1-4%. So it makes business sense to harvest CBD from Hemp as oppose to Marijuana, and it is legal in all 50 states to do so.

hemp leaf

Industrial Hemp

In the US, “industrial hemp” is classified by the federal government as cannabis containing no more than 0.3% THC by dry weight. This classification was established in the 2018 Farm Bill and was refined to include hemp-sourced extracts, cannabinoids, and derivatives in the definition of hemp.  

More importantly, the THC cannabinoid is the one that will produce the euphoric effect on the mind. The hemp plant only containing 0.3% of THC it would make it impossible to get high from this plant or any CBD harvested from the plant. The bottom line is you need to get your CBD manufactured from Hemp to for it to be legal and for no “high” effect to take place. Most of the higher quality companies will take their hemp process a step further and strain out even the slightest amounts of THC from the Hemp plant.

Conversely, Hemp extracted CBD can actually lessen or neutralize the psychoactive effects of THC, depending on how much of each compound is consumed. Consequently, most people want the health benefits of cannabis without the high effect so they can maintain day to day activities as usual.

At MD Organics we have verifiable and viewable third party lab results demonstrating that all our products are THC Free.


The major confusion surrounding the “high” effect is that both Hemp and Marijuana plants come from the same family of Cannabis plants. But that is where the similarity ends. The appearance, caring, and harvesting are totally different. Moreover, the CBD itself from both plants will not get you high nor can it. It is only when it is coupled with THC in the marijuana plant that the user could get a high effect. CBD itself actually helps counteract the effects of THC.


CBD works within your Endocannabinoid System or ECS. Newly discovered in the 1990’s by researchers exploring THC, this system has two receptors called CB1 and CB2. These receptor sites are scattered throughout your body. CB1 receptors are mostly found in your central nervous system. CB2 receptors are mostly found in your peripheral nervous system and most of these are located in your immune system.

In fact, few people know that your body actually produces some Cannabinoids on its own. Endogenous Cannabinoids are neurotransmitters produced within our bodies that bind to cannabinoid receptors in the brain, immune system, and elsewhere. Examples include virodhamine (OAE), n-arachidonoyl dopamine (NADA), arachidonoylglyceral (2-AG), and anadamide.

Now, how CBD works is by activating or inhibiting these receptor sites and by doing so helps to regulate many homeostasis functions. THC directly binds to these CB1 and CB2 receptors, whereas CBD indirectly targets these receptors.

For Example, look at as if CBD was a door, blocking an intruder from getting in your house, or allowing a welcomed friend into your home. By blocking bad compounds from entering your cells or allowing beneficial compounds to enter, you are allowing your body to function as it should with optimal results. But because of our bad western diets, most people are depleted in vital nutrients in the body that CBD contains. This is where CBD benefits the user in helping for a specific issue or overall wellness.


  • CBD itself will never get you high.
  • Only using a CBD oil from the marijuana plant could get you high.
  • THC is the cannabinoid that causes the high effect.
  • The Hemp plant produces tiny amounts (0.3%) of THC and it is why it is Federally Legal based on the 2018 Farm Bill.
  • CBD is more abundant in Hemp, while low levels are in Marijuana.
  • THC levels in Hemp are 0.3% or less, while Marijuana is 10-30%.
  • Hemp CBD is what you will want to take when choosing the CBD Oil that is best for you.

You now have the knowledge of what CBD Oil is and what it is not. More importantly, that it will not get you High or have any mind altering negative effects. Learn More Here!

Not Sure how much CBD to take, Click Here!



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